Herald of Technological University Herald of Technological University ВЕСТНИК ТЕХНОЛОГИЧЕСКОГО УНИВЕРСИТЕТА 3034-4689 62593 ХИМИЯ, ТЕХНОЛОГИЯ И ИСПОЛЬЗОВАНИЕ ПОЛИМЕРОВ ХИМИЯ, ТЕХНОЛОГИЯ И ИСПОЛЬЗОВАНИЕ ПОЛИМЕРОВ Kinetics and mechanism of poly(3-hydroxybutyrate) degradation Bonartsev A P Bonartsev A P Boskhomodgiev A P Boskhomodgiev A P Iordanskii A L Iordanskii A L Bonartseva G A Bonartseva G A Rebrov A V Rebrov A V Makhina T K Makhina T K Myshkina V L Myshkina V L Yakovlev S A Yakovlev S A Filatova E A Filatova E A Ivanov E A Ivanov E A Bagrov D V Bagrov D V Zaikov G E Zaikov G E ov_stoyanov@mail.ru Artsis M I Artsis M I A.N.Bach's Institute of Biochemistry, Russian Academy of Sciences ru A.N.Bach's Institute of Biochemistry, Russian Academy of Sciences ru A.N.Bach's Institute of Biochemistry, Russian Academy of Sciences ru A.N.Bach's Institute of Biochemistry, Russian Academy of Sciences ru A.N.Bach's Institute of Biochemistry, Russian Academy of Sciences ru A.N.Bach's Institute of Biochemistry, Russian Academy of Sciences ru A.N.Bach's Institute of Biochemistry, Russian Academy of Sciences ru A.N.Bach's Institute of Biochemistry, Russian Academy of Sciences ru A.V.Topchiev Institute of Petroleum Chemistry ru A.V.Topchiev Institute of Petroleum Chemistry ru A.N.Bach's Institute of Biochemistry, Russian Academy of Sciences ru A.N.Bach's Institute of Biochemistry, Russian Academy of Sciences ru A.N.Bach's Institute of Biochemistry, Russian Academy of Sciences ru A.N.Bach's Institute of Biochemistry, Russian Academy of Sciences ru A.N.Bach's Institute of Biochemistry, Russian Academy of Sciences ru A.N.Bach's Institute of Biochemistry, Russian Academy of Sciences ru A.N.Bach's Institute of Biochemistry, Russian Academy of Sciences ru A.N.Bach's Institute of Biochemistry, Russian Academy of Sciences ru A.N.Bach's Institute of Biochemistry, Russian Academy of Sciences ru A.N.Bach's Institute of Biochemistry, Russian Academy of Sciences ru Moscow State University ru Moscow State University ru Kazan National Research Technological University ru Kazan National Research Technological University ru Emanuel Institute of Biochemical Physics of Russian Academy of Sciences ru Emanuel Institute of Biochemical Physics of Russian Academy of Sciences ru 01 08 2025 01 08 2025 17 4 145 151 20 04 2023 https://vestniktu.ru/en/nauka/article/62593/view

Работа посвящена биоразлагаемому поли(3-гидроксибутирату) и исследованию его производных. Исследована кинетика гидролитического разложения при 37 и 70 oС в фосфатном буфере для сравнения кинетических профилей ПЛЛ и ПГБ. Кроме того, изучена кинетика для сополимера ПГБВ (20% 3-гидроксивалерата) и смеси ПГБ-ПЛЛ. Интенсивность гидролиза биополимера характеризуется общей потерей массы и уменьшением усредненной молекулярной массы (MМ). Разложение усиливается в серии ПГБВ <ПГБ< смесь ПГБ-ПЛЛ <PLA. Характеристики ПГБ и ПГБВ включают ММ и изменение кристалличности (дифракции рентгеновских лучей), а также АСМ-анализ поверхности ПГБ-пленок до и после экспозиции в агрессивной среде. Показано влияние ММ на гидролиз биополимера.

This work is designed to be an informative source for biodegradable poly(3-hydroxybutyrate) and its derivatives’ research. We focuses on hydrolytic degradation kinetics at 37 and 70 oC in phosphate buffer to compare PLA and PHB kinetic profiles. Besides, we reveal the kinetic behavior for copolymer PHBV (20% of 3-hydroxyvalerate) and the blend PHB-PLA. The intensity of biopolymer hydrolysis characterized by total weight lost and the viscosity-averaged molecular weight (MW) decrement. The degradation is enhanced in the series PHBV < PHB < PHB-PLA blend < PLA. Characterization of PHB and PHBV includes MW and crystallinity evolution (x-ray diffraction) as well as AFM analysis of PHB film surfaces before and after aggressive medium exposition. The important impact of MW on the biopolymer hydrolysis is shown.

 Bacterial poly(3-hydroxybutyrate) copolymer PHBV polylactide PHB-PLA blend non-enzymatic hydrolysis role of molecular weight crystallinity total weight loss WAXS AMF бактериальный поли(3-гидроксибутират) сополимер ПГБВ полилактид смесь ПГБ-ПЛЛ без-ферментативный гидролиз роль молекулярной массы кристалличность общая потеря массы метод WAXS АСМ Bacterial poly(3-hydroxybutyrate) copolymer PHBV polylactide PHB-PLA blend non-enzymatic hydrolysis role of molecular weight crystallinity total weight loss WAXS AMF бактериальный поли(3-гидроксибутират) сополимер ПГБВ полилактид смесь ПГБ-ПЛЛ без-ферментативный гидролиз роль молекулярной массы кристалличность общая потеря массы метод WAXS АСМ

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