<?xml version="1.0"?>
<!DOCTYPE article
PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.4 20190208//EN"
       "JATS-journalpublishing1.dtd">
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.4" xml:lang="en">
 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">Herald of Technological University</journal-id>
   <journal-title-group>
    <journal-title xml:lang="en">Herald of Technological University</journal-title>
    <trans-title-group xml:lang="ru">
     <trans-title>ВЕСТНИК ТЕХНОЛОГИЧЕСКОГО УНИВЕРСИТЕТА</trans-title>
    </trans-title-group>
   </journal-title-group>
   <issn publication-format="print">3034-4689</issn>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="publisher-id">60858</article-id>
   <article-categories>
    <subj-group subj-group-type="toc-heading" xml:lang="ru">
     <subject>БИОХИМИЯ И БИОТЕХНОЛОГИЯ</subject>
    </subj-group>
    <subj-group subj-group-type="toc-heading" xml:lang="en">
     <subject></subject>
    </subj-group>
    <subj-group>
     <subject>БИОХИМИЯ И БИОТЕХНОЛОГИЯ</subject>
    </subj-group>
   </article-categories>
   <title-group>
    <article-title xml:lang="en">СОВЕРШЕНСТВОВАНИЕ ТЕХНОЛОГИИ ПРОИЗВОДСТВА СУХОЙ ЖИВОЙ ВАКЦИНЫ ПРОТИВ САЛЬМОНЕЛЛЕЗА ТЕЛЯТ</article-title>
    <trans-title-group xml:lang="ru">
     <trans-title>СОВЕРШЕНСТВОВАНИЕ ТЕХНОЛОГИИ ПРОИЗВОДСТВА СУХОЙ ЖИВОЙ ВАКЦИНЫ ПРОТИВ САЛЬМОНЕЛЛЕЗА ТЕЛЯТ</trans-title>
    </trans-title-group>
   </title-group>
   <contrib-group content-type="authors">
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Павленко</surname>
       <given-names>И В</given-names>
      </name>
      <name xml:lang="en">
       <surname>Павленко</surname>
       <given-names>И В</given-names>
      </name>
     </name-alternatives>
     <email>polt65@yandex.ru</email>
     <xref ref-type="aff" rid="aff-1"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Самуйленко</surname>
       <given-names>А Я</given-names>
      </name>
      <name xml:lang="en">
       <surname>Самуйленко</surname>
       <given-names>А Я</given-names>
      </name>
     </name-alternatives>
     <email>vnitibp@mail.ru</email>
     <xref ref-type="aff" rid="aff-2"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Еремец</surname>
       <given-names>В И</given-names>
      </name>
      <name xml:lang="en">
       <surname>Еремец</surname>
       <given-names>В И</given-names>
      </name>
     </name-alternatives>
     <email>biv_74@mail.ru</email>
     <xref ref-type="aff" rid="aff-3"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Бобровская</surname>
       <given-names>И В</given-names>
      </name>
      <name xml:lang="en">
       <surname>Бобровская</surname>
       <given-names>И В</given-names>
      </name>
     </name-alternatives>
     <email>biv_74@mail.ru</email>
     <xref ref-type="aff" rid="aff-4"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Нежута</surname>
       <given-names>А А</given-names>
      </name>
      <name xml:lang="en">
       <surname>Нежута</surname>
       <given-names>А А</given-names>
      </name>
     </name-alternatives>
     <email>vnitibp@mail.ru</email>
     <xref ref-type="aff" rid="aff-5"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Канарская</surname>
       <given-names>З А</given-names>
      </name>
      <name xml:lang="en">
       <surname>Канарская</surname>
       <given-names>З А</given-names>
      </name>
     </name-alternatives>
     <email>zosya_kanarskaya@mail.ru</email>
     <xref ref-type="aff" rid="aff-6"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Канарский</surname>
       <given-names>А В</given-names>
      </name>
      <name xml:lang="en">
       <surname>Канарский</surname>
       <given-names>А В</given-names>
      </name>
     </name-alternatives>
     <email>alb46@mail.ru</email>
     <xref ref-type="aff" rid="aff-7"/>
    </contrib>
   </contrib-group>
   <aff-alternatives id="aff-1">
    <aff>
     <institution xml:lang="ru">ГНУ ВНИТИБП РАСХН РФ</institution>
     <country>ru</country>
    </aff>
    <aff>
     <institution xml:lang="en">ГНУ ВНИТИБП РАСХН РФ</institution>
     <country>ru</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-2">
    <aff>
     <institution xml:lang="ru">ГНУ ВНИТИБП РАСХН РФ; РАСХН</institution>
     <country>ru</country>
    </aff>
    <aff>
     <institution xml:lang="en">ГНУ ВНИТИБП РАСХН РФ; РАСХН</institution>
     <country>ru</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-3">
    <aff>
     <institution xml:lang="ru">ГНУ ВНИТИБП РАСХН РФ</institution>
     <country>ru</country>
    </aff>
    <aff>
     <institution xml:lang="en">ГНУ ВНИТИБП РАСХН РФ</institution>
     <country>ru</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-4">
    <aff>
     <institution xml:lang="ru">ГНУ ВНИТИБП РАСХН РФ</institution>
     <country>ru</country>
    </aff>
    <aff>
     <institution xml:lang="en">ГНУ ВНИТИБП РАСХН РФ</institution>
     <country>ru</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-5">
    <aff>
     <institution xml:lang="ru">ГНУ ВНИТИБП РАСХН РФ</institution>
     <country>ru</country>
    </aff>
    <aff>
     <institution xml:lang="en">ГНУ ВНИТИБП РАСХН РФ</institution>
     <country>ru</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-6">
    <aff>
     <institution xml:lang="ru">КНИТУ</institution>
     <country>ru</country>
    </aff>
    <aff>
     <institution xml:lang="en">КНИТУ</institution>
     <country>ru</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-7">
    <aff>
     <institution xml:lang="ru">КНИТУ</institution>
     <country>ru</country>
    </aff>
    <aff>
     <institution xml:lang="en">КНИТУ</institution>
     <country>ru</country>
    </aff>
   </aff-alternatives>
   <pub-date publication-format="print" date-type="pub" iso-8601-date="2025-08-01T13:16:05+03:00">
    <day>01</day>
    <month>08</month>
    <year>2025</year>
   </pub-date>
   <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2025-08-01T13:16:05+03:00">
    <day>01</day>
    <month>08</month>
    <year>2025</year>
   </pub-date>
   <volume>16</volume>
   <issue>8</issue>
   <fpage>226</fpage>
   <lpage>231</lpage>
   <history>
    <date date-type="received" iso-8601-date="2023-04-19T18:14:53+03:00">
     <day>19</day>
     <month>04</month>
     <year>2023</year>
    </date>
   </history>
   <self-uri xlink:href="https://vestniktu.ru/en/nauka/article/60858/view">https://vestniktu.ru/en/nauka/article/60858/view</self-uri>
   <abstract xml:lang="ru">
    <p>Оптимизированы питательная среда и параметры периодического глубинного культивирования штамма Salmonella dublin № 160, способствующие накоплению микробных клеток в культуральной среде. Разработана защитная среда для высушивания сальмонелл. Результаты исследований использованы при разработке технологии производства сухой живой вакцины против сальмонеллеза телят. </p>
   </abstract>
   <trans-abstract xml:lang="en">
    <p>Optimized culture medium and the parameters of periodic deep cultivation of the strain Salmonella dublin № 160, causing the accumulation of microbial cells in the culture medium. Developed a protective environment for drying Salmonella. The results of the studies were used in the development of production technology of dry live vaccine against Salmonella calves. </p>
   </trans-abstract>
   <kwd-group xml:lang="ru">
    <kwd>Salmonella dublin № 160</kwd>
    <kwd>периодическое глубинное культивирование</kwd>
    <kwd>концентрирование</kwd>
    <kwd>защитная среда</kwd>
    <kwd>сушка</kwd>
    <kwd>вакцина</kwd>
    <kwd>Salmonella dublin № 160</kwd>
    <kwd>periodic deep cultivation</kwd>
    <kwd>concentration</kwd>
    <kwd>protective environment drying</kwd>
    <kwd>the vaccine</kwd>
   </kwd-group>
   <kwd-group xml:lang="en">
    <kwd>Salmonella dublin № 160</kwd>
    <kwd>периодическое глубинное культивирование</kwd>
    <kwd>концентрирование</kwd>
    <kwd>защитная среда</kwd>
    <kwd>сушка</kwd>
    <kwd>вакцина</kwd>
    <kwd>Salmonella dublin № 160</kwd>
    <kwd>periodic deep cultivation</kwd>
    <kwd>concentration</kwd>
    <kwd>protective environment drying</kwd>
    <kwd>the vaccine</kwd>
   </kwd-group>
  </article-meta>
 </front>
 <body>
  <p></p>
 </body>
 <back>
  <ref-list>
   <ref id="B1">
    <label>1.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">В.Н. Выдрин, И.А. Шевцов, А.А. Маслак, А.С. Мащенко. Ветеринария. № 1. С.66 (1998).</mixed-citation>
     <mixed-citation xml:lang="en">V.N. Vydrin, I.A. Shevcov, A.A. Maslak, A.S. Maschenko. Veterinariya. № 1. S.66 (1998).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B2">
    <label>2.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Н.И. Землянская. Благовещенск: ДальГАУ, С. 56 - 59 (2004).</mixed-citation>
     <mixed-citation xml:lang="en">N.I. Zemlyanskaya. Blagoveschensk: Dal'GAU, S. 56 - 59 (2004).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B3">
    <label>3.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">А.В. Иванов, Л.В. Королёва, М.Г. Нигматулин, Л.Р. Гузенфельд. Ветеринарный врач. № 3. С. 38 (2000).</mixed-citation>
     <mixed-citation xml:lang="en">A.V. Ivanov, L.V. Koroleva, M.G. Nigmatulin, L.R. Guzenfel'd. Veterinarnyy vrach. № 3. S. 38 (2000).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B4">
    <label>4.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Н.Н. Сагабиева. Автореф. дисс. канд. вет. наук. Казань, 2004. 27 с.</mixed-citation>
     <mixed-citation xml:lang="en">N.N. Sagabieva. Avtoref. diss. kand. vet. nauk. Kazan', 2004. 27 s.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B5">
    <label>5.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Hardman, P. M., Wathes, C. M., &amp; Wray, C. (1991). Transmission of salmonellae among calves penned individually. Veterinary Record, 129, 327-329.</mixed-citation>
     <mixed-citation xml:lang="en">Hardman, P. M., Wathes, C. M., &amp; Wray, C. (1991). Transmission of salmonellae among calves penned individually. Veterinary Record, 129, 327-329.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B6">
    <label>6.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Houe, H., Ersbøll, A.K., &amp; Toft. N. (2004) Introduction to Veterinary Epidemiology, 1st edition. Eds. Houe, H., Ersbøll, A.K., &amp; Toft, N. Biofolia, Frederiksberg, Denmark.</mixed-citation>
     <mixed-citation xml:lang="en">Houe, H., Ersbøll, A.K., &amp; Toft. N. (2004) Introduction to Veterinary Epidemiology, 1st edition. Eds. Houe, H., Ersbøll, A.K., &amp; Toft, N. Biofolia, Frederiksberg, Denmark.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B7">
    <label>7.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">House, J. K. &amp; Smith, B. P. (2004). Profitable Strategies to Control Salmonellosis in Dairy Cattle. In: Proceedings of WBC Congress, 23rd 352 World Buiatric Congress, Québec, Canada.</mixed-citation>
     <mixed-citation xml:lang="en">House, J. K. &amp; Smith, B. P. (2004). Profitable Strategies to Control Salmonellosis in Dairy Cattle. In: Proceedings of WBC Congress, 23rd 352 World Buiatric Congress, Québec, Canada.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B8">
    <label>8.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Jordan, D., Nielsen, L. R., &amp; Warnick, L. D. (2008). Modelling a national programme for the control of foodborne pathogens in livestock: the case of Salmonella Dublin in the Danish cattle industry. Epidemiology and Infection, 136, 1521-1536.</mixed-citation>
     <mixed-citation xml:lang="en">Jordan, D., Nielsen, L. R., &amp; Warnick, L. D. (2008). Modelling a national programme for the control of foodborne pathogens in livestock: the case of Salmonella Dublin in the Danish cattle industry. Epidemiology and Infection, 136, 1521-1536.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B9">
    <label>9.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">А.А. Раевский. Материалы Международной научно-практической конференции «Научные основы производства ветеринарных биологических препаратов». Щелково, С. 61-64. (2003).</mixed-citation>
     <mixed-citation xml:lang="en">A.A. Raevskiy. Materialy Mezhdunarodnoy nauchno-prakticheskoy konferencii «Nauchnye osnovy proizvodstva veterinarnyh biologicheskih preparatov». Schelkovo, S. 61-64. (2003).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B10">
    <label>10.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">А.А. Раевский, А.Я. Самуйленко. Материалы Международной научно-практической конференции «Фармацевтические и медицинские биотехнологии». М., С. 291 - 292 (2012).</mixed-citation>
     <mixed-citation xml:lang="en">A.A. Raevskiy, A.Ya. Samuylenko. Materialy Mezhdunarodnoy nauchno-prakticheskoy konferencii «Farmacevticheskie i medicinskie biotehnologii». M., S. 291 - 292 (2012).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B11">
    <label>11.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">А.Я. Самуйленко, Е.А. Рубан. Основы биотехнологии производства биологических препаратов. (Теоретические основы, оборудование, технологические линии). М., 782 с. (2000).</mixed-citation>
     <mixed-citation xml:lang="en">A.Ya. Samuylenko, E.A. Ruban. Osnovy biotehnologii proizvodstva biologicheskih preparatov. (Teoreticheskie osnovy, oborudovanie, tehnologicheskie linii). M., 782 s. (2000).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B12">
    <label>12.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Mizuno, T., McLennan, M., &amp; Trott, D. (2008). Intramuscular vaccination of young calves with a Salmonella Dublin metabolic-drift mutant provides superior protection to oral delivery. Veterinary Research, 39, 26.</mixed-citation>
     <mixed-citation xml:lang="en">Mizuno, T., McLennan, M., &amp; Trott, D. (2008). Intramuscular vaccination of young calves with a Salmonella Dublin metabolic-drift mutant provides superior protection to oral delivery. Veterinary Research, 39, 26.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B13">
    <label>13.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">В., Бирюков, В.М. Кантере. Оптимизация периодических процессов микробиологического синтеза. М., Наука, 293с. (1985).</mixed-citation>
     <mixed-citation xml:lang="en">V., Biryukov, V.M. Kantere. Optimizaciya periodicheskih processov mikrobiologicheskogo sinteza. M., Nauka, 293s. (1985).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B14">
    <label>14.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">В.М. Кантере Теоретические основы технологии микробиологических производств. М., Агропромиздат. 272 с. (1991)</mixed-citation>
     <mixed-citation xml:lang="en">V.M. Kantere Teoreticheskie osnovy tehnologii mikrobiologicheskih proizvodstv. M., Agropromizdat. 272 s. (1991)</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B15">
    <label>15.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">А.А. Нежута, Э.Ф. Токарик, А.Я. Самуйленко, В.М. Безгин, Е.С. Сербис Теоретические и практические основы технологии сублимационного высушивания биопрепаратов. Курск. Изд-во Курской гос. сельскох. академии. 240 с. (2002)</mixed-citation>
     <mixed-citation xml:lang="en">A.A. Nezhuta, E.F. Tokarik, A.Ya. Samuylenko, V.M. Bezgin, E.S. Serbis Teoreticheskie i prakticheskie osnovy tehnologii sublimacionnogo vysushivaniya biopreparatov. Kursk. Izd-vo Kurskoy gos. sel'skoh. akademii. 240 s. (2002)</mixed-citation>
    </citation-alternatives>
   </ref>
  </ref-list>
 </back>
</article>
