Herald of Technological University Herald of Technological University ВЕСТНИК ТЕХНОЛОГИЧЕСКОГО УНИВЕРСИТЕТА 3034-4689 63010 БИОХИМИЯ, БИОТЕХНОЛОГИЯ И ЭКОЛОГИЯ БИОХИМИЯ, БИОТЕХНОЛОГИЯ И ЭКОЛОГИЯ SURFACE-MODIFIED MAGNETIC NANOPARTICLES FOR CELL LABELING Zasonska B A Zasonska B A gezaikov@yahoo.com Patsula V Patsula V gezaikov@yahoo.com Stoika R Stoika R gezaikov@yahoo.com Horák D Horák D gezaikov@yahoo.com Zaikov G E Zaikov G E gezaikov@yahoo.com Shkodich V F Shkodich V F shkodich@mail.ru Kochnev A M Kochnev A M kochnev55@bk.ru Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic ru Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic ru Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic ru Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic ru National Academy of Science of Ukraine ru National Academy of Science of Ukraine ru Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic ru Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic ru Institute of Biochemical Physics, RAS, Moscow, Russia ru Institute of Biochemical Physics, RAS, Moscow, Russia ru Department of technology of synthetic rubber ru Department of technology of synthetic rubber ru Department of technology of synthetic rubber ru Department of technology of synthetic rubber ru 01 08 2025 01 08 2025 17 8 194 200 20 04 2023 https://vestniktu.ru/en/nauka/article/63010/view

Cинтезированы два типа наночастиц оксида железа (g-Fe 2O 3) и (Fe 3O 4). В этой работе, поверхность, образованных наночастиц опсонизированная с белками, находящимися в эмбриональной телячьей сыворотки крови. Показано, что синтезированные магнитные наночастицы γ-Fe 2O 3@PDMAAm и γ-Fe 2O 3@SiO 2, нецитотоксические и интенсивно фагоцитируются на макрофагах млекопитающих.

There were synthesized two different types of iron oxide nanoparticles, maghemite (g-Fe 2O 3) and magnetite (Fe 3O 4). In this work, surface of the formed nanoparticles was opsonized with proteins available in the fetal bovine blood serum. The γ-Fe 2O 3@PDMAAm and γ-Fe 2O 3@SiO 2 nanoparticles, in contrast to the neat nanoparticles were shown to be non-cytotoxic and intensively phagocytozed by the mammalian macrophages.

magnetic nanoparticles surface modification colloidal particles ATR FTIR spectroscopy cell labeling магнитные наночастицы поверхностная модификация коллоидные частицы НПВО ИК-спектроскопия клеточные маркеры magnetic nanoparticles surface modification colloidal particles ATR FTIR spectroscopy cell labeling магнитные наночастицы поверхностная модификация коллоидные частицы НПВО ИК-спектроскопия клеточные маркеры

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