Herald of Technological University Herald of Technological University ВЕСТНИК ТЕХНОЛОГИЧЕСКОГО УНИВЕРСИТЕТА 3034-4689 63632 ХИМИЯ, ТЕХНОЛОГИЯ И ИСПОЛЬЗОВАНИЕ ПОЛИМЕРОВ ХИМИЯ, ТЕХНОЛОГИЯ И ИСПОЛЬЗОВАНИЕ ПОЛИМЕРОВ HIGH-MOLECULAR WEIGHT BIOPOLYMER Омер А М Omer A M Ahmedomer_81@yahoo.com.com Тэймер Т М Tamer T M Ahmedomer_81@yahoo.com.com Мохельдин M S Mohyeldin M S Ahmedomer_81@yahoo.com.com Шкодич В Ф Shkodich V F shkodich@mail.ru Кочнев А М Коchnev А М kochnev55@bk.ru Научно-исследовательский институт передовых технологий и новых материалов (ПТНМНИИ), Город научных исследований и технологических применений (НИТП-город), Александрия, Египет ru Advanced Technologies and New Materials Research Institute (ATNMRI), City of Scientific Research and Technological Applications (SRTA- City), Alexandria, Egypt ru Научно-исследовательский институт передовых технологий и новых материалов (ПТНМНИИ), Город научных исследований и технологических применений (НИТП-город), Александрия, Египет ru Advanced Technologies and New Materials Research Institute, City of Scientific Research and Technological Applications, Alexandria, Egypt ru Научно-исследовательский институт передовых технологий и новых материалов (ПТНМНИИ), Город научных исследований и технологических применений (НИТП-город), Александрия, Египет ru Advanced Technologies and New Materials Research Institute, City of Scientific Research and Technological Applications, Alexandria, Egypt ru КНИТУ ru KNRTU ru КНИТУ ru KNRTU ru 01 08 2025 01 08 2025 17 14 241 250 20 04 2023 https://vestniktu.ru/en/nauka/article/63632/view

Гиалуроновая кислота (ГК) является высокомолекулярным, линейным полисахаридом и присутствует во всех тканях и жидкостях организмов высших животных. Превосходные свойства ГК, такие как биологическое разложение, биосовместимость, безопасность, отличная мукоадгезивная способность и высокая способность удерживать воду, делают ее высокоэффективной для использования в различных биомедицинских приложениях. Кроме того; ГК нетоксичная, противовоспалительная и неиммуногенная. Из всех этих преимуществ, ГК получила большое внимание как матрица для системы доставки лекарств. В данном обзоре будут обобщены современные знания о ГК, о ее свойствах и развитии в некоторых фармацевтических приложениях.

Hyaluronan (HA) is a high-molecular weight, naturally occurring linear polysaccharide and found in all tissues and body fluids of higher animals. The excellent properties of HA such as biodegradability, biocompatibility, safety, excellent mucoadhesive capacity and high water retaining ability make it well-qualified for using in various bio-medical applications. In addition; HA is non-toxic, non-inflammatory and non-immunogenic. Because of all these advantages, HA has received much attention as a matrix for drug delivery system. This review will summarize our present knowledge about HA, properties and its development in some pharmaceutical applications.

Hyaluronan Drug delivery system Hydrogel Antioxidant гиалуронан гидрогель антиоксидант система переноса лекарств Hyaluronan Drug delivery system Hydrogel Antioxidant гиалуронан гидрогель антиоксидант система переноса лекарств

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