A SUSTAINABLE AND EFFICIENT APPROACH TO BROMOETHAN SYNTHESIS
Rubrics: 2. CHEMICAL TECHNOLOGY
Authors:
1.
LLC "R D "AkhmadullinS"
(Engineer)
from 01.01.2016 to 01.01.2023
Kazan', Kazan, Russian Federation
from 01.01.2016 to 01.01.2023
Kazan', Kazan, Russian Federation
2.
OOO NTC «Ahmadulliny»
3.
KNITU
4.
KNITU
5.
OOO NTC "Ahmadulliny"
6.
Kazan National Research Technological University
7.
Kazan State Technological University
(Department of Chemistry and Technology of Elastomer Processing, Student)
student from 01.01.2022 until now
Russian Federation
student from 01.01.2022 until now
Russian Federation
Type:
Article
Pages:
from 41
to 48
Status:
Published
Received:
31.01.2026
Accepted:
31.01.2026
Published:
31.01.2026
Language:
English
Keywords:
ETHYL BROMIDE, RESIDUAL AQUEOUS ACID SOLUTION, THIOLS, REGENERATED SODIUM BROMIDE
Abstract:
An optimized and sustainable method for the synthesis of ethyl bromide (C2H5Br) via the reaction of ethanol with a halide salt (KBr/NaBr) in the presence of concentrated sulfuric acid (H2SO4) has been presented. The molar ratios of 1:1.2:2:5, 1:1.2:4.5:11.2, and 1:2:3.5:13.2 (KBr/NaBr: C2H5OH:H2SO4: H2O) depending on the order of reagent mixing were found to favor higher yields. In addition, other factors like synthesis duration, temperature and catalyst were also studied. The overall maximum achieved yield was 93-95%. To address the large excess of acid when a molar ratio 1:1.2:4.5:11.2 and 1:2:3.5:13.2 is used, a closed-loop recycling approach was introduced: the residual aqueous acid solution from the first synthesis was reused in subsequent batches by adjusting the H2SO4, stoichiometry to 1.1-2.1 equivalents, minimizing waste without compromising efficiency. In order to save the cost of the reagents, especially the halide salts for the synthesis process and address environmental risks associated with the discharge of sodium bromide as a byproduct, regenerated sodium bromide from a classical method of thiol synthesis process was utilized in the preparation of ethyl bromide under same conditions which also resulted in obtaining high yields. The effectiveness of the synthesis process using sodium bromide solution has also been presented. The obtained product from sodium bromide solution also exhibited high purity profile same as the product obtained from commercial halide salts. The product was isolated by simple distillation and characterized by gas chromatography and boiling point confirming high purity. The presented results has also shown the potential application of the synthesis process at a larger scale.
An optimized and sustainable method for the synthesis of ethyl bromide (C2H5Br) via the reaction of ethanol with a halide salt (KBr/NaBr) in the presence of concentrated sulfuric acid (H2SO4) has been presented. The molar ratios of 1:1.2:2:5, 1:1.2:4.5:11.2, and 1:2:3.5:13.2 (KBr/NaBr: C2H5OH:H2SO4: H2O) depending on the order of reagent mixing were found to favor higher yields. In addition, other factors like synthesis duration, temperature and catalyst were also studied. The overall maximum achieved yield was 93-95%. To address the large excess of acid when a molar ratio 1:1.2:4.5:11.2 and 1:2:3.5:13.2 is used, a closed-loop recycling approach was introduced: the residual aqueous acid solution from the first synthesis was reused in subsequent batches by adjusting the H2SO4, stoichiometry to 1.1-2.1 equivalents, minimizing waste without compromising efficiency. In order to save the cost of the reagents, especially the halide salts for the synthesis process and address environmental risks associated with the discharge of sodium bromide as a byproduct, regenerated sodium bromide from a classical method of thiol synthesis process was utilized in the preparation of ethyl bromide under same conditions which also resulted in obtaining high yields. The effectiveness of the synthesis process using sodium bromide solution has also been presented. The obtained product from sodium bromide solution also exhibited high purity profile same as the product obtained from commercial halide salts. The product was isolated by simple distillation and characterized by gas chromatography and boiling point confirming high purity. The presented results has also shown the potential application of the synthesis process at a larger scale.
Keywords:
ETHYL BROMIDE, RESIDUAL AQUEOUS ACID SOLUTION, THIOLS, REGENERATED SODIUM BROMIDE
ETHYL BROMIDE, RESIDUAL AQUEOUS ACID SOLUTION, THIOLS, REGENERATED SODIUM BROMIDE
