Studied the effect of halogenated furanone on Staphylococcus aureus resistance to heat shock. It is shown that the investigated furanone supposedly reduces virulence of Staphylococcus aureus and enhances the effect of heat shock on the cells.
галогенированные фураноны, Staphylococcus aureus, тепловой шок, физиологическая активность, halogenated furanones, Staphylococcus aureus, heat shock, physiological activity
1. Kluytmans, J. Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks [Text] / J. Kluytmans, A. van Belkum, H. Verbrugh // Clin Microbiol Rev. 1997. P. 503.
2. Servant, P. Negative regulation of the heat shock response in Streptomyces [Text] / P. Servant, P. Mazodier // Arch Microbiol. - 2001. - V.176 - P.237-242.
3. Basnak'yan, I.A. Stress u bakteriy [Tekst] / I. A. Basnak'yan // M.: Medicina, 2003. - S.9-14.
4. Lengler, Y. Sovremennaya mikrobiologiya. Prokarioty [Tekst] : [per. s angl] / Y. Lengler, G. Drevs, G. Shlegel'. - Moskva: Mir, 2005. - 656s. - Perevod izd: Biology of the prokaryotes / Joseph W. Lengeler, Gerhard Drews, Hans G. Schlegel. - Stuttgart: Blackwell Science, 1999.
5. Pokrovskiy, V. I. Medicinskaya mikrobiologiya [Tekst] / V. I. Pokrovskiy, O. K. Pozdeev - Moskva: GEOTAR Medicina, 1998. - 416s.
6. Belonogova, N.V. Gomoserinlakton kak modulyator funkcional'noy aktivnosti kletok prokariot [Tekst] / N.V. Belonogova, A.B. Margulis, V.Ya. Ponomarev, A.I. Kolpakov, O.N. Il'inskaya // Vestnik Kazanskogo tehnologicheskogo universiteta.2012.T.15, №23.S.109-113.
7. Mit'ko, V.E. Proizvodnye furanonov kak ingibitory plotnostno-zavisimyh processov u bakteriy [Tekst] / V.E. Mit'ko, A.V. Garusov, O.N. Il'inskaya, A.B. Margulis // "Vestnik Ural'skoy medicinskoy akademicheskoy nauki" (Tematicheskiy vypusk po mikrobiologii, immunologii i biotehnologii).2011.№4/1(38).S. 41.
8. Margulis, A.B. Vliyanie hlorproizvodnyh 2(5N)-furanona na zhiznesposobnost' bakterial'nyh kletok [Tekst] / A.B. Margulis, A.R. Kurbangalieva, N.V. Belonogova, L.Z. Latypova, V.Ya. Ponomarev, E.N. Hakimullina, E.Yu. Trizna, M.I. Bogachev, A.R. Kayumov // Vestnik Kazanskogo tehnologicheskogo universiteta.2012.T. 15, №15.S. 220-224.
9. Mit'ko, V.E. Toksicheskie i genotoksicheskie effekty novyh sintezirovannyh furanonov i ih galogenirovannyh proizvodnyh [Tekst] / V.E. Mit'ko, A.B. Margulis, V.Ya. Ponomarev, A.I. Kolpakov, O.N. Il'inskaya // Vestnik Kazanskogo tehnologicheskogo universiteta.2013.T.16, №11.S.211-213.
