EKSPERIMENTAL'NOE I TEORETICHESKOE ISSLEDOVANIE RASTVORIMOSTI METILPARABENA I IBUPROFENA V SVERHKRITICHESKOM DIOKSIDE UGLERODA NA IZOTERME T=308 K
Abstract and keywords
Abstract (English):
In this paper, an experimental setup that allows you to measure the solubility of substances in supercritical fluids in a wide range of temperature and pressure. In this work, the solubility of methyl paraben and ibuprofen in the pressure range of 10 - 30 MPa at a temperature of 308 K. It was established experimentally that an increase in the system pressure increases the solubility of the test substances. It was revealed that the solubility of ibuprofen is an order of solubility of methyl paraben. Mathematically described by the solubility of ibuprofen and methylparaben in the approximation of the equation of state Peng-Robinson. The results show the agreement between the experimental and calculated data.

Keywords:
растворимость, метилпарабен, ибупрофен, диоксид углерода, сверхкритический флюид, уравнение состояния Пенга-Робинсона, Solubility methylparaben, ibuprofen, carbon dioxide supercritical fluid state equation Peng-Robinson
References

1. Kuznecova, I.V. Dispergirovanie farmacevticheskih preparatov, polimernyh materialov s ispol'zovaniem sverhkriticheskih flyuidnyh sred / I.V. Kuznecova, I.M. Gil'mutdinov, A.N. Sabirzyanov i dr.// Vestnik Kazanskogo tehnologicheskogo universiteta.-2010.-№2.-S.321-328

2. Qunsheng, Li. Solubility of solid solutes in supercritical carbon dioxide with and without cosolvents / Li Qunsheng, Zhang Zeting, Zhong Chongli, Liu Yancheng, Zhou Qingrong // Departament of Chemical Engineering, Beijing University of Chemical Technology, P.O. Box 100, Beijing 100029, China.-accepted 14 January 2003

3. Gil'mutdinov I.I. Rastvorimost' ibuprofena v sverhkriticheskom diokside ugleroda / I.I. Gil'mutdinov, I.V. Kuznecova, I.M. Gil'mutdinov, A.A. Muhamadiev, A.N. Sabirzyanov // Sverhkriticheskie flyuidy - teoriya i praktika. - 2012. t.7. - №3.

Login or Create
* Forgot password?