The AKR mice of age 3-4 months were exposed to 137Cs g-irradiation with doses of 1.2-2.4 cGy for 2-4 days at a dose- rate of 0.6 cGy/day. S-shaped curve of survivals (percent of live animals-age) for the control (intact animals) and experimental (exposed) groups were obtained. The curves were approximated by the Hompertz function. The rate of development of the malignant process was determined by the modal age (the inflection point on the curve of survivals) when the death rate in a population reaches a maximum (mode). The irradiation of animals produced a promoting effect (approximately by a factor of 1.3) on the development of malignant process. The average and maximum of lifespans decreased approximately by 20 and 120 days, respectively.
malignant tumors, irradiation, злокачественные опухоли, облучение
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