It was studied properties of S-, O-aniones generated from 6-methyl-2-thiouracil in water-dioxane solutions. Structures of S- and O-aniones and energy of reaction were investigated by quantum-chemical calculations. Reactivity of S- and O-aniones in nucleofilic substituation of halogen in halogen substituted compaundes (R=Hal: Hal = Cl, Br, I; R = Et, Pr, All, Bn, p-adamantil Bn, m-phenoxy Bn, o-,p-Br Bn) was tested by kinetic methode. We worked out synthesis of S-mono- and S,O-disubstituted 6-methyl-2-thiouraciles ( max yield is 99.8 %).
синтез S-моно- и S-,О-дипроизводных, 6-метил-2-тио-, 2-алкил(аралкил)тиоурацил, квантово-химический анализ, метод AB INITIO, S-mono- and S-,O-disubstituted, 6-methyl-2-thiouraciles, quantum chemical analysis, method AB INITIO
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