Studied several synthesis methods 2,2 I-bisimidazol, including cyclization, dehydrogenation,dehydrobromination. It is shown that the most efficient of these is the interaction of glycosalsulfat with ammonia. A convenient method for purifying 2,2 I-bisimidazol through its sulfate.
имидазол, бисимидазол, циклизация, глиоксаль, глиоксальсульфат, дегидрирование, imidazole, bisimidazol, cyclization, glyoxal, glioksalsulfat, dehydrogenation
1. F.G. Hayrutdinov, G.P. Sharnin, R.Z. Gil'manov, Z.G. Ahtyamova, Vestnik Kazan. tehnol. un-ta, 15, 7, 46-47 (2012).
2. Z.G. Ahtyamova, R.Z. Gimanov, I.F. Falyahov,Vestnik Kazan.tehnolog.un-ta, 15 , 12, 23-25 (2012).
3. H. Debus, Ann.,107, 199-203 (1858).
4. L. P. Kyrides, F. B. Lienty, G. W. Steanly, H. L. Morril, J. Org. Chem, 12, 577 (1947).
5. M. Ya. Kraft, P. M. Kochergin, A. M. Cyganova, V. S. Shluhunova, I. A. Kuznecova, E. N. Alekseeva, Avt.svid.SSSR, № 201418, RZhHIM, 1968, 19N356P.
6. H. A. Green, pat. SShA 3037028, 29.05.62. S. A., 57, 1250 (1962); W.E. Erner, pat. SShA, 2847147;S.A., 53, 4306 (1953).
7. G. Forssel, Ber., 24, 1846 (1891). J. Wang, J. E. Bauma. Jnorgan. Chem., 4, 1613 (1965).
8. I.I. Grandberg, A.N. Kost, ZhOH, 28, 307 (1958).
9. B.M. Barclay, N. Campbell, J. Chem. Soc., 1945, 530.
10. Th. Cutius, J. prakt. Chem., [2], 50, 531 (1894).
11. W. Markwald, Ber., 25, 2354 (1892); A. Kreutzberger, J. Org. Chem., 27, 886 (1962); H. Bredereck, R. Grommper, K. Klemm, H. Rempfer, Ber., 92, 844 (1959).
12. B. Storey, W. Sullivan, C. Moyer, J. Org. Chem., 29, 3118 (1964).
13. P. Ruggli, E. Henzi, Helv. Chem. Acta, 12, 362(1929).
