THE BIOCOMPATIBILITY OF POLYMERS BASED ON 2-HYDROXYETHYL METHACRYLATE FOR CREATION OF NEW EMBOLIZATION MATERIALS POSSESSED OF TRANSPORT FUNCTION
Abstract and keywords
Abstract (English):
The embolization material (EM) based on poly-HEMA has been successfully used for the treatment of certain tumor (ischemia of liver tumors, kidney, myomatous nodes, etc). Ethyleneglycol dimethacrylate (EGDMA) has been using as the cross-linking agent. A possibility of using cross-linking agents different in qualitative and quantitative structure of allows modifying physical and chemical properties of the resulting synthesized hydrogels. It was developed of syntheses of poly-HEMA with use tri-ethyleneglycol dimethacrylate (tri-EGDMA) and tetra-ethyleneglycol dimethacrylate (tetra-EGDMA) as cross-lynking agents. The present study has been aimed at investigating the possibility of using tri-EGDMA and tetra-EGDMA as cross-linking agents as well as the research of the morphological structure of the polymers, their biocompatibility and hemostatic effect.

Keywords:
biocompatibility, dimethacrylate glycols, hemostatic effect, leukopenia, poly-HEMA, Romanowsky-Giemsa, биологическая совместимость, гликоли диметакрилата, кровоостанавливающее действие, лейкопения, ПГЭМА, Романовский-Гимза
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